Why You Need PDRN Skincare in Your Routine: Desembre Dermagarden Serum & Cream Explained
- maria ramos
- May 18
- 3 min read

If you’re serious about investing in your skin’s health—especially when it comes to firmness, repair, and long-term glow—then it’s time you learned about PDRN and why the Desembre Dermagarden PDRN Serum and Cream deserve a permanent spot in your routine.
These two Korean skincare formulas are packed with next-generation ingredients and backed by skin science, making them ideal for anyone dealing with aging, dullness, dehydration, or barrier damage.
Let’s break down exactly what makes these products so special—and who they’re perfect for.
What Is PDRN and Why Does It Matter?
PDRN (polydeoxyribonucleotide) is a DNA compound originally derived from salmon DNA—yes, salmon! It’s become a buzzed-about ingredient in Korean and medical aesthetics for its ability to:
Regenerate skin cells
Improve skin elasticity
Boost healing and repair
Enhance skin thickness and hydration
PDRN works by encouraging the natural production of new cells and collagen, helping the skin recover faster from inflammation, fine lines, breakouts, or environmental stress. It’s especially helpful after advanced facials or chemical peels, when the skin needs extra support.
Desembre Dermagarden PDRN Serum: Lightweight Powerhouse
This serum is like a reset button for tired, dull skin. It has a featherlight texture but is packed with deeply restorative ingredients that absorb quickly and get to work fast.
Key Benefits:
Boosts radiance and skin vitality
Improves fine lines and wrinkles
Re-energizes the skin with cell-repairing PDRN
Supports healing and barrier repair—especially after peels or breakouts
Notable Ingredients:
Sodium DNA (PDRN): For deep regeneration and elasticity
Niacinamide: Brightens skin and strengthens the moisture barrier
Centella Asiatica: Soothes inflammation and supports collagen production
Adenosine: Reduces visible signs of aging
This serum is ideal for anyone who wants immediate glow with long-term skin strengthening. It layers beautifully under your moisturizer and can be used both morning and night.

Desembre Dermagarden PDRN Cream: Rich, Nourishing & Firming
While the serum jumpstarts your glow, this cream locks in the benefits and adds intensive repair. It uses the same formula as the popular Desembre PDRN Core Vital Cream, just in new packaging.
Why You’ll Love It:
Deeply hydrates without clogging pores
Strengthens damaged or compromised skin
Firms, plumps, and softens fine lines over time
Calms redness and irritation with healing botanical extracts
Hero Ingredients:
Niacinamide: Locks in moisture and brightens dull tone
Snail Secretion Filtrate: Repairs the skin and enhances texture
Centella Asiatica: Firms and soothes
sr-Spider Polypeptide-1: Forms a protective moisture barrier
DNA (PDRN): Revives tired, aging skin at the cellular level
Natural plant extracts: Add antioxidant protection and balance
This cream is great for dry, sensitive, or aging skin, and also perfect post-treatment when the skin needs serious TLC.
Who Should Use These Products?
These formulas are gentle enough for sensitive skin but powerful enough to deliver clinical-level results. They’re perfect for:
Those dealing with wrinkles, dullness, or sagging
Clients with post-treatment or post-acne healing needs
Skin that feels dry, irritated, or over-exfoliated
Anyone starting to see early signs of aging
The Bottom Line
Desembre Dermagarden’s PDRN line is all about reviving your skin from the inside out. Whether you’re treating aging skin, repairing after advanced treatments, or just wanting that bouncy, radiant glow—we’re obsessed with this duo for a reason.
At The Beauty Plug, we’ve started integrating both products into our facial recovery protocols and offering them for at-home care so clients can maintain their glow between visits.
Ready to Try It?
Come shop with us at The Beauty Plug in Valley Village or ask about these in your next appointment. We’ll help you build the perfect post-facial skincare routine with pro-grade Korean skincare that works.
📍 Valley Village, CA🌐 www.thebeautyplugbymaria.com


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